Article

Retinal and Optic Nerve Lesions Correspond to Amyloid in Autosomal Dominant Alzheimer’s Disease

2025-01-22

Abstract excerpt

Autosomal dominant Alzheimer’s disease (ADAD) is a rare form of Alzheimer’s disease (AD) in which the biology of the disease can be explored during the presymptomatic phase of the illness. The retina is an outgrowth of the central nervous system and therefore provides the opportunity for direct observation of neural tissue and its vasculature during life. Retinal thinning measured in vivo has been previously descr...

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Literature Corpus work: 19f5963a-f791-5a0e-9531-cf42212851f5
DOI: 10.1101/2025.01.21.25319904

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