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A translatable evaluation tool to study the biodistribution of clinically-available doxorubicin liposomes: PET imaging of [ <sup>89</sup> Zr]Zr-Doxil and [ <sup>89</sup> Zr]Zr-Talidox

2025-06-23

Abstract excerpt

<h4>INTRODUCTION</h4> Doxil/Caelyx is a PEGylated liposomal formulation of the chemotherapeutic doxorubicin used in the clinic for Kaposi’s sarcoma, advanced ovarian cancer, progressive multiple myeloma and metastatic breast cancer. Talidox ® , a smaller doxorubicin PEGylated liposome is undergoing clinical trials and has been proposed as an improvement on previous liposomal formulations for the treatment of adv...

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Literature Corpus work
19ebe446-cf54-5c79-bcf8-05d977720941
DOI
10.1101/2025.06.17.660144
Open publication

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A translatable evaluation tool to study the biodistribution of clinically-available doxorubicin liposomes: PET imaging of [ <sup>89</sup> Zr]Zr-Doxil and [ <sup>89</sup> Zr]Zr-TalidoxDOI 10.1101/2025.06.17.660144
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