Article

Multi-curie Production of Gallium-68 on a Biomedical Cyclotron and Automated Radiolabelling of PSMA-11 and DOTATATE

2020-09-22

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>With increasing clinical demand for gallium-68, commercial germanium-68/gallium-68 ([<sup>68</sup>Ge]Ge/[<sup>68</sup>Ga]Ga) generators are incapable of supplying sufficient amounts of the short-lived daughter isotope. In this study, we demonstrate a high-yield, automated method for producing multi-Curie levels of [<sup>68</sup>Ga]GaCl<sub>3</sub> from solid zin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: fcf4c39e-472b-5a4a-8f90-21951c42d861
DOI: 10.21203/rs.3.rs-78850/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-curie Production of Gallium-68 on a Biomedical Cyclotron and Automated Radiolabelling of PSMA-11 and DOTATATEDOI 10.21203/rs.3.rs-78850/v1Read

Multi-Curie Production of Gallium-68 on a Biomedical Cyclotron and Automated Radiolabelling of PSMA-11 and DOTATATESemantic proximity Read

Cyclotron-based production of 68Ga, [68Ga]GaCl3, and [68Ga]Ga-PSMA-11 from a liquid targetSemantic proximity Read

Fully Automated Production of [68Ga]FAPI-46 with Gallium-68 from Cyclotron Using Liquid TargetsSemantic proximity Read

GMP-conform production of [ 68Ga ]Ga-NeoB for positron emission tomography imaging of patients with gastrointestinal stromal tumorSemantic proximity Read

Monte Carlo prediction and experimental characterisation of long-lived waste byproducts arising from cyclotron production of zirconium-89 utilising a commercially available yttrium foilSemantic proximity Read

A Comparison of Routine [68Ga]Ga-PSMA-11 Preparation using Locametz and Illuccix KitsSemantic proximity Read

Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [68Ga]Ga-ABY-025 tracerSemantic proximity Read

Feasibility and Safety of 68Ga-PSMA-11 PET/CT Using Cyclotron-Produced 68Ga in Patients with Prostate CancerSemantic proximity Read

Bismuth-213 for Targeted Radionuclide Therapy: From Atom to BedsideSemantic proximity Read

Biomedical Applications of Targeted Drug Delivery, Nanotheranostic and Nuclear MedicineSemantic proximity Read

Automated Production of [<sup>68</sup>Ga]Ga-desferrioxamine B on Two Different Synthesis PlatformsSemantic proximity Read

High‑yield, standardised automated radiosynthesis process for routine clinical insulinoma PET with [⁶⁸Ga]Ga‑NODAGA‑exendin‑4Semantic proximity Read