Article

High-dose methylprednisolone mediates YAP/TAZ-TEAD in vocal fold fibroblasts with macrophages

2024-07-19

Abstract excerpt

<title>Abstract</title> <p>The pro-fibrotic effects of glucocorticoids may lead to a suboptimal therapeutic response for vocal fold (VF) pathology. Targeting macrophage-fibroblast interactions is an interesting therapeutic strategy; macrophages alter their phenotype to mediate both inflammation and fibrosis. In the current study, we investigated concentration-dependent effects of methylprednisolone on the fibroti...

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Literature Corpus work: 19e6f660-17a0-5057-99f3-a58b46355ede
DOI: 10.21203/rs.3.rs-4626638/v1

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