Article

Controlled decorin delivery from injectable microgels promotes scarless vocal fold repair

2025-06-28

Abstract excerpt

Vocal fold (VF) scarring is a leading cause of poor voice, yet no therapies exist to prevent its progression. Current treatments, such as intracordal steroid injections, offer limited efficacy and carry significant off-target toxicities. To identify targeted anti-scarring strategies, we performed transcriptomics of human VF myofibroblasts, the cellular drivers of VF scarring, and identified the proteoglycan decori...

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Literature Corpus work: f6c83ef8-4a02-5f2b-ae43-59565fedc6f9
DOI: 10.1101/2025.06.25.661429

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