Article
Paracrine Effects of Adipose-Derived Cellular Therapies in an in Vitro Fibrogenesis Model of Human Vocal Fold Scarring.
Journal of voice : official journal of the Voice Foundation - 1 Nov 2024
Velier Mélanie, Mattei Alexia, Simoncini Stéphanie, Magalon Jérémy, Giraudo Laurent, Arnaud Laurent, Giovanni Antoine, Dignat-George Francoise, Sabatier Florence, Gugatschka Markus, Grossmann Tanja
Abstract excerpt
OBJECTIVES/HYPOTHESIS: Vocal folds (VF) scarring leads to severe dysphonia which negatively impacts daily life of patients. Current therapeutic options are limited due in large part to the high complexity of the micro-structure of the VF. Innovative therapies derived from adipose tissue such as stromal vascular fraction (SVF) or adipose derived stromal/ stem cells (ASC) are currently being evaluated in this...
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