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Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge

2020-06-25

Abstract excerpt

<h4>Background: </h4> Long noncoding RNAs (lncRNAs) are considered critical regulators in cancers; however, the clinical significance and mechanisms of MAPKAPK5-AS1 (hereinafter referred to as MK5-AS1) in colorectal cancer (CRC) remain mostly unknown. <h4>Methods:</h4> In this study, quantitative real-time PCR ( qPCR ) and western blotting were utilized to detect the levels of MK5-AS1, let-7f-1-3p and MK5 (MAPK ac...

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Literature Corpus work
2319a706-62a7-5574-a2a5-6cd1aaf1fcd0
DOI
10.21203/rs.3.rs-21081/v3
Open publication

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