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Article

MELK is an oncogenic kinase essential for early hepatocellular carcinoma recurrence.

Cancer letters - 1 Dec 2016

Xia Hongping, Kong Shik Nie, Chen Jianxiang, Shi Ming, Sekar Karthik, Seshachalam Veerabrahma Pratap, Rajasekaran Muthukumar, Goh Brian Kim Poh, Ooi London Lucien, Hui Kam M

Abstract excerpt

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. Many kinases have been found to be intimately involved in oncogenesis and the deregulation of kinase function has emerged as a major mechanism by which cancer cells evade normal physiological constraints on growth and survival. Previously, we have performed gene expression profile analysis on HCC samples and have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27693640
DOI: 10.1016/j.canlet.2016.09.017

Genes

MELK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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