Article

CITE-seq analysis reveals human cytomegalovirus and diabetes-associated adaptive NK cell alterations in cardiovascular disease

2024-03-26

Abstract excerpt

Coronary artery disease (CAD) is a leading cause of mortality worldwide with Diabetes and human cyto-megalovirus (HCMV) infection as risk factors. CAD’s influence on human NK cells is not well characterized. CITE-seq analysis of a CAD cohort of 61 patients revealed distinctly higher NK cell SPON2 expression and lower IFNG expression in severe CAD patients. Interestingly, HCMV + patients displayed lower SPON2 e...

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Literature Corpus work: 19c67ec9-a8ae-56c7-a4c4-cfce5e30576e
DOI: 10.1101/2024.03.22.581997

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