Article
Genetic and Functional Profiling of CD16-Dependent Natural Killer Activation Identifies Patients at Higher Risk of Cardiac Allograft Vasculopathy.
Circulation - 6 Mar 2018
Paul Pascale, Picard Christophe, Sampol Emmanuelle, Lyonnet Luc, Di Cristofaro Julie, Paul-Delvaux Louise, Lano Guillaume, Nicolino-Brunet Corinne, Ravis Eleonore, Collart Frederic, Dignat-George Francoise, Dussol Bertrand, Sabatier Florence, Mouly-Bandini Annick
Abstract excerpt
BACKGROUND: Cardiac transplantation is an effective therapy for end-stage heart failure. Because cardiac allograft vasculopathy (CAV) is the major cause of late mortality after heart transplant (HT), there is a need to identify markers that reflect inflammatory or cytotoxic immune mechanisms contributing to its onset. Noninvasive and early stratification of patients at risk remains a challenge for adapting...
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