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Spatially resolved transcriptomics reveals a unique disease signature and potential biomarkers for chronic traumatic encephalopathy

2025-04-26

Abstract excerpt

Chronic traumatic encephalopathy (CTE) is a poorly understood environmental tauopathy uniquely associated with repetitive head injury. It is clinically ambiguous, and at present can only be diagnosed post-mortem. There is a pressing need to understand CTE pathophysiology in order to identify targets for possible intervention and biomarkers for in-life diagnosis, however molecular characterisation of the disease is...

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Literature Corpus work
19b1165b-51a5-502e-bbbc-f12583241e0e
DOI
10.1101/2025.04.23.650359
Open publication

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Spatially resolved transcriptomics reveals a unique disease signature and potential biomarkers for chronic traumatic encephalopathyDOI 10.1101/2025.04.23.650359
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