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Article

Coordinated Changes in Gene Expression Kinetics Underlie both Mouse and Human Erythroid Maturation

2020-12-22

Abstract excerpt

<h4>Background</h4> Single cell technologies are transforming biomedical research, including the recent demonstration that unspliced pre-mRNA present in single cell RNA-Seq permits prediction of future expression states. Here we applied this ‘RNA velocity concept’ to an extended timecourse dataset covering mouse gastrulation and early organogenesis. <h4>Results</h4> Intriguingly, RNA velocity correctly identifie...

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Literature Corpus work
19a16278-bdbc-5a66-8dee-f02b073c5938
DOI
10.1101/2020.12.21.423773
Open publication

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Coordinated Changes in Gene Expression Kinetics Underlie both Mouse and Human Erythroid MaturationDOI 10.1101/2020.12.21.423773
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