Article
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Nature genetics - 1 Apr 2015
Onengut-Gumuscu Suna, Chen Wei-Min, Burren Oliver, Cooper Nick J, Quinlan Aaron R, Mychaleckyj Josyf C, Farber Emily, Bonnie Jessica K, Szpak Michal, Schofield Ellen, Achuthan Premanand, Guo Hui, Fortune Mary D, Stevens Helen, Walker Neil M, Ward Lucas D, Kundaje Anshul, Kellis Manolis, Daly Mark J, Barrett Jeffrey C, Cooper Jason D, Deloukas Panos, Todd John A, Wallace Chris, Concannon Patrick, Rich Stephen S
Abstract excerpt
Genetic studies of type 1 diabetes (T1D) have identified 50 susceptibility regions, finding major pathways contributing to risk, with some loci shared across immune disorders. To make genetic comparisons across autoimmune disorders as informative as possible, a dense genotyping array, the Immunoc...
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