Article

Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization

2020-07-15

Abstract excerpt

In vitro antibody selection against pathogens from naïve combinatorial libraries can yield various classes of antigen-specific binders that are distinct from those evolved from natural infection 1–4 . Also, rapid neutralizing antibody discovery can be made possible by a strategy that selects for those interfering with pathogen and host interaction 5 . Here we report the discovery of antibodies that neutralize SA...

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Literature Corpus work: 0f276e26-6671-5c63-bffe-652d396417f1
DOI: 10.1101/2020.07.14.203414

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