Article
Artificial Intelligence-Powered Discovery of Small Molecules Inhibiting CTLA-4 in Cancer
2023-07-10
Abstract excerpt
Checkpoint inhibitors, which generate durable responses in many cancer patients, have revolutionized cancer immunotherapy. However, their therapeutic efficacy is limited, and immune-related adverse events are very sever, especially for monoclonal antibody treatment directed against cytotoxic T-lymphocyte–associated protein 4 (CTLA-4), which plays a pivotal role in preventing autoimmunity and fostering anticancer i...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 18f83c4b-d8d4-5d48-967a-6007e4990a5b
- DOI
- 10.21203/rs.3.rs-3131433/v1