Article

MetaChrome: An Open-Source, User-Friendly Tool for Automated Metaphase Chromosome Analysis

2025-09-07

Abstract excerpt

DNA Fluorescence In Situ Hybridization (FISH) is an essential technique to study chromosome biology and genetics, enabling precise visualization of specific genomic loci to study structural abnormalities, gene mapping, and chromosomal rearrangements. High-Throughput Imaging (HTI) can automate the analysis of DNA-FISH chromosome images, but the accurate and automated segmentation of mitotic chromosomes and simultan...

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Literature Corpus work: c86fddb9-e386-56cf-abc1-e2b6f4d609e1
DOI: 10.1101/2025.09.02.673813

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