Article

A filter-flow perspective of hematogenous metastasis offers a non-genetic paradigm for personalized cancer therapy

2013-11-07

Abstract excerpt

<h4>Background: </h4> Research into mechanisms of hematogenous metastasis has largely become genetic in focus, attempting to understand the molecular basis of `seed-soil' relationships. However, preceding this biological mechanism is the physical process of dissemination of circulating tumour cells (CTCs) in the circulatory network. We utilize a novel, network perspective of hematogenous metastasis and a large dat...

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Literature Corpus work: 1872ab9b-d918-52b1-bb1d-325cfaa1d717
DOI: 10.1101/000125

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