Article

Aging drives a program of DNA methylation decay in plant organs

2024-11-05

Abstract excerpt

How organisms age is a question with broad implications for human health. In mammals, DNA methylation is a biomarker for biological age, which may predict age more accurately than date of birth. However, limitations in mammalian models make it difficult to identify mechanisms underpinning age-related DNA methylation changes. Here, we show that the short-lived model plant Arabidopsis thaliana exhibits a loss of ep...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 186034aa-c583-5909-8768-ad0585552cfc
DOI: 10.1101/2024.11.04.621941

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Aging drives a program of DNA methylation decay in plant organsDOI 10.1101/2024.11.04.621941Read

Aging drives a program of DNA methylation decay in plant organs.Semantic proximity Read

Stage-specific transcriptomes and DNA methylomes indicate an early and transient loss of transposon control in Arabidopsis shoot stem cellsSemantic proximity Read

Repeat elements and the Arabidopsis DNA methylation landscape.Semantic proximity Read

DDM1 guards against telomere truncation in Arabidopsis.Semantic proximity Read

A role for RNAi in the selective correction of DNA methylation defects.Semantic proximity Read

Age-associated alterations in the somatic mutation and DNA methylation levels in plants.Semantic proximity Read

Transgenerational stability of the Arabidopsis epigenome is coordinated by CG methylation.Semantic proximity Read

Transposon age and non-CG methylation.Semantic proximity Read

A DNA break-5mC cycle activates transposable elements in Arabidopsis.Semantic proximity Read

Stable transgenerational epigenetic inheritance requires a DNA methylation-sensing circuit.Semantic proximity Read

Exploring the Relationship of Transposable Elements and Ageing: Causes and ConsequencesSemantic proximity Read

Chromatin-modifying genetic interventions suppress age-associated transposable element activation and extend life span in Drosophila.Semantic proximity Read