Article
DDM1 guards against telomere truncation in Arabidopsis.
Plant cell reports - 1 Mar 2018
Xie Xiaoyuan, Shippen Dorothy E
Abstract excerpt
KEY MESSAGE: Prolonged hypomethylation of DNA leads to telomere truncation correlated with increased telomere recombination, transposon mobilization and stem cell death. Epigenetic pathways, including DNA methylation, are crucial for telomere maintenance. Deficient in DNA Methylation 1 (DDM1) encodes a nucleosome remodeling protein, required to maintain DNA methylation in Arabidopsis thaliana. Plants lacking DDM1...
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