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Article

Analysis of Bulk RNA Sequencing Data Reveals Novel Transcription Factors Associated With Immune Infiltration Among Multiple Cancers.

Frontiers in immunology - 1 Jan 2021

Liu Lei, Zhao Qiuchen, Cheng Chao, Yi Jingwen, Sun Hongyan, Wang Qi, Quan Weili, Xue Yaqiang, Sun Luguo, Cong Xianling, Zhang Yi

Abstract excerpt

Tumor-infiltrating immune cells shape the tumor microenvironment and are closely related to clinical outcomes. Several transcription factors (TFs) have also been reported to regulate the antitumor activity and immune cell infiltration. This study aimed to quantify the populations of different immune cells infiltrated in tumor samples based on the bulk RNA sequencing data obtained from 50 cancer patients using the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34489925
DOI: 10.3389/fimmu.2021.644350
PMCID: PMC8417605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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