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Article

Retroviruses facilitate the rapid evolution of the mammalian placenta.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 2013

Chuong Edward B

Abstract excerpt

The mammalian placenta exhibits elevated expression of endogenous retroviruses (ERVs), but the evolutionary significance of this feature remains unclear. I propose that ERV-mediated regulatory evolution was, and continues to be, an important mechanism underlying the evolution of placental development. Many recent studies have focused on the co-option of ERV-derived genes for specific functional adaptations in the...

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Share to Endogenous Retroviruses
Share to Enhancer Elements, Genetic
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammals

Share to Placenta

Share to Regulatory Sequences, Nucleic Acid

Share to Terminal Repeat Sequences

Share to Trophoblasts

Source

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Identifiers

PMID: 23873343
DOI: 10.1002/bies.201300059
PMCID: PMC4332834

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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