Article

pheno-seq – linking morphological features to gene expression in 3D cell culture systems

2018-05-01

Abstract excerpt

3D-culture systems have advanced cancer modeling by reflecting physiological characteristics of in-vivo tissues, but our understanding of functional intratumor heterogeneity including visual phenotypes and underlying gene expression is still limited. Single-cell RNA-sequencing is the method of choice to dissect transcriptional tumor cell heterogeneity in an unbiased way, but this approach is limited in correlatin...

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Literature Corpus work: 1823c560-a19b-5b74-8eab-47b92fd653be
DOI: 10.1101/311472

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