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Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cells

2024-11-21

Abstract excerpt

Oxidised low-density lipoprotein cholesterol (ox-LDL) is critical in the initiation and progression of atherosclerosis. While excessive atherogenic lipids in the arterial intima can trigger endothelial dysfunction in advanced lesions, the response of endothelial cells to ox-LDL in the early stages of atherogenesis remains unclear. Here, we conducted a comprehensive, genome-wide multi-omics characterisation of the...

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Literature Corpus work
17f2fb85-014e-5a5c-9f9b-366bfe8b4a3a
DOI
10.1101/2024.11.19.624299
Open publication

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Ox-LDL induces a non-inflammatory response enriched for coronary artery disease risk in human endothelial cellsDOI 10.1101/2024.11.19.624299
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