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Article

The Role of Endothelial Cells in Atherosclerosis: Insights from Genetic Association Studies.

The American journal of pathology - 1 Apr 2024

Pepin Mark E, Gupta Rajat M

Abstract excerpt

Endothelial cells (ECs) mediate several biological functions that are relevant to atherosclerosis and coronary artery disease (CAD), regulating an array of vital processes including vascular tone, wound healing, reactive oxygen species, shear stress response, and inflammation. Although which of these functions is linked causally with CAD development and/or progression is not yet known, genome-wide association...

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Identifiers

PMID: 37827214
DOI: 10.1016/j.ajpath.2023.09.012
PMCID: PMC10988759

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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