Article

Evolution of interface binding strengths in simplified model of protein quaternary structure

2019-02-21

Abstract excerpt

The self-assembly of proteins into protein quaternary structures is of fundamental importance to many biological processes, and protein misassembly is responsible for a wide range of proteopathic diseases. In recent years, abstract lattice models of protein self-assembly have been used to simulate the evolution and assembly of protein quaternary structure, and to provide a tractable way to study the genotype-pheno...

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Literature Corpus work: 17d75f62-80da-56ce-96a6-0f43b920720c
DOI: 10.1101/557272

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