Modelling neutral and selective evolution of protein folding.

doi:10.1098/rspb.1991.0081

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Article

Modelling neutral and selective evolution of protein folding.

Proceedings. Biological sciences - 22 Jul 1991

Lipman D J, Wilbur W J

Abstract excerpt

We examine a model evolutionary space consisting of genotypes mapped to their corresponding phenotypes. This mapping is derived from a lattice model for proteins which, despite its highly idealized nature, has been shown to share general properties with real proteins. Large evolutionary networks...

Topics

Biological Evolution
Genotype
Models, Genetic
Mutation
Phenotype
Protein Conformation
Proteins
Selection, Genetic

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