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Article

Age-dependent evolution of the yeast protein interaction network suggests a limited role of gene duplication and divergence.

PLoS computational biology - 1 Nov 2008

Kim Wan Kyu, Marcotte Edward M

Abstract excerpt

Proteins interact in complex protein-protein interaction (PPI) networks whose topological properties-such as scale-free topology, hierarchical modularity, and dissortativity-have suggested models of network evolution. Currently preferred models invoke preferential attachment or gene duplication and divergence to produce networks whose topology matches that observed for real PPIs, thus supporting these as likely...

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Identifiers

PMID: 19043579
DOI: 10.1371/journal.pcbi.1000232
PMCID: PMC2583957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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