Article

Bacterial exo-α-sialidases subvert the complement system through desialylation

2026-02-05

Abstract excerpt

<h4>SUMMARY</h4> The complement system is a central pillar of innate immunity, yet how bacterial glycan-modifying enzymes subvert complement function remains poorly understood. Bacterial sialidases remove terminal sialic acids from host sialoglycans, but their direct impact on complement immunity is unclear. Here, we investigate the impact of six sialidases from five human pathogens on complement immunity using a...

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Literature Corpus work: 17bb7962-2b4a-56cb-8da3-767063850382
DOI: 10.64898/2026.02.05.703967

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