Article

Bipolar filaments of human nonmuscle myosin 2-A and 2-B have distinct motile and mechanical properties

2017-10-23

Abstract excerpt

Nonmuscle myosin 2 (NM-2) powers cell motility and tissue morphogenesis by assembling into bipolar filaments that interact with actin. Although the enzymatic properties of purified NM-2 motor fragments have been determined, the emergent properties of filament ensembles are unknown. Using single myosin filament in vitro motility assays, we report fundamental differences in filaments formed of different NM-2 motors...

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Literature Corpus work: 17b15491-575b-5249-a01f-f389150042bc
DOI: 10.1101/207514

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