Article
Growth, lifetime, directional movement and myosin-dependent motility of mutant keratin granules in cultured cells.
Scientific reports - 27 Jan 2021
Lehmann S M, Leube R E, Windoffer R
Abstract excerpt
Intermediate filament polypeptides (IFPs) are prominent components of cytoplasmic aggregates, which are pathognomonic for multiple diseases. Recent observations in cultured cells suggest that they are dynamic and subject to regulated turnover. The emerging concept is that multiple factors contribute to motility and turnover of IFP-containing aggregates. To understand their relative contribution, quantitative...
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