Article

Targets of the human antibody response to the variant surface glycoprotein of <i>Trypanosoma brucei</i>

2025-09-25

Abstract excerpt

Human African Trypanosomiasis (HAT) is a severe disease endemic to Sub-Saharan Africa caused by the parasite Trypanosoma brucei . Diagnosis of the chronic form of HAT relies heavily on serological screening tests that detect specific antibodies. Trypanosoma brucei parasites rely on the antigenic variation of their variant surface glycoproteins (VSG) to evade host antibody recognition. Although VSG is the primary...

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Literature Corpus work: 179f7c5a-6b36-5119-8132-73698d6159fd
DOI: 10.1101/2025.09.25.678491

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