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Key mutations on spike protein altering ACE2 receptor utilization and potentially expanding host range of emerging SARS-CoV-2 variants

2022-04-11

Abstract excerpt

Increasing evidence supports inter-species transmission of SARS-CoV-2 variants from human to domestic or wild animals during the ongoing COVID-19 pandemic, which is posing great challenges to epidemic control. Clarifying the host range of emerging SARS-CoV-2 variants will provide instructive information for the containment of viral spillover. The spike protein (S) of SARS-CoV-2 is the key determinant of receptor u...

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Literature Corpus work
1762283c-9cf5-5a8d-8ea3-ecc3c6da231b
DOI
10.1101/2022.04.11.487828
Open publication

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Key mutations on spike protein altering ACE2 receptor utilization and potentially expanding host range of emerging SARS-CoV-2 variantsDOI 10.1101/2022.04.11.487828
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