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Article

Key mutations on spike protein altering ACE2 receptor utilization and potentially expanding host range of emerging SARS-CoV-2 variants.

Journal of medical virology - 1 Jan 2023

Wang Qiong, Ye Sheng-Bao, Zhou Zhi-Jian, Li Jin-Yan, Lv Ji-Zhou, Hu Bodan, Yuan Shuofeng, Qiu Ye, Ge Xing-Yi

Abstract excerpt

Increasing evidence supports inter-species transmission of SARS-CoV-2 variants from humans to domestic or wild animals during the ongoing COVID-19 pandemic, which is posing great challenges to epidemic control. Clarifying the host range of emerging SARS-CoV-2 variants will provide instructive information for the containment of viral spillover. The spike protein (S) of SARS-CoV-2 is the key determinant of receptor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36056469
DOI: 10.1002/jmv.28116
PMCID: PMC9538830

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