Article

Pro-tumor and prothrombotic activities of hepsin in colorectal cancer cells and suppression by venetoclax

2022-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Hepsin is a type II transmembrane serine protease whose expression has been linked to greater tumorigenicity and worse prognosis in different tumors such as prostate and gastric cancer. Recently, our group described hepsin expression in the primary biopsy as a potential biomarker of thrombosis and metastasis in localized colorectal cancer patients. Here we explored the role of hepsin in this tum...

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Literature Corpus work: 1721e14a-aa3c-5060-8c70-f256a4429c39
DOI: 10.1101/2022.10.01.510038

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