Article
Genes associated with venous thromboembolism in colorectal cancer patients.
Journal of thrombosis and haemostasis : JTH - 1 Feb 2018
Ünlü B, van Es N, Arindrarto W, Kiełbasa S M, Mei H, Westerga J, Middeldorp S, Kuppen P J K, Otten J M M B, Cannegieter S, Versteeg H H
Abstract excerpt
Essentials The underlying pathophysiological mechanisms behind cancer-associated thrombosis are unknown. We compared expression profiles in tumor cells from patients with and without thrombosis. Tumors from patients with thrombosis showed significant differential gene expression profiles. Patients with thrombosis had a proinflammatory status and increased fibrin levels in the tumor. SUMMARY: Background Venous...
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