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Exposure to PFOA and GenX elicits cell type-specific impacts on p53 and TGF-β signaling pathways

2025-05-03

Abstract excerpt

Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals extensively used as plastic additives. Their environmental persistence and potential for bioaccumulation have raised significant toxicological concerns. This study evaluates the cytotoxic and molecular effects of Perfluorooctanoic acid (PFOA) and its replacement compound, Perfluoro(2-methyl-3-oxohexanoic) acid (GenX), in human-derived sk...

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Literature Corpus work
16f1a757-e734-5df5-92cb-32a40bb27659
DOI
10.1101/2025.05.03.652004
Open publication

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Exposure to PFOA and GenX elicits cell type-specific impacts on p53 and TGF-β signaling pathwaysDOI 10.1101/2025.05.03.652004
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