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Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term culture

2021-04-17

Abstract excerpt

<h4>ABSTRACT</h4> Body fat depots are heterogeneous concerning their embryonic origin, structure, exposure to environmental stressors, and availability. Thus, investigating adipose-derived mesenchymal stromal cells (ASCs) from different sources is essential to standardization for future therapies. In vitro amplification is also critical because it may predispose cell senescence and mutations, reducing regenerati...

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Literature Corpus work
16e9774c-28e1-591d-a85e-6420eaedaaf4
DOI
10.1101/2021.04.16.440228
Open publication

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Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term cultureDOI 10.1101/2021.04.16.440228
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