Article

Comparison of senescence-related changes between three- and two-dimensional cultured adipose-derived mesenchymal stem cells

2020-05-15

Abstract excerpt

<title>Abstract</title> <p>Background: Adipose-derived mesenchymal stem cells ( ADMSCs ) have attracted widespread interest as cell-based tissue repair systems. To obtain adequate quantities of ADMSCs for therapeutic applications, extensive in vitro expansion is required. However, under current two-dimensional (2D) approaches , ADMSCs rapidly undergo replicative senescence , and cell growth is impeded and stem ce...

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Literature Corpus work: 3647143d-0d63-51e6-b4de-cebfd3fea5f9
DOI: 10.21203/rs.3.rs-15404/v2

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