Article

Mitochondria-derived vesicles deliver antimicrobial payload to control phagosomal bacteria

2018-03-05

Abstract excerpt

<h4>Summary</h4> Pathogenic bacteria taken up into the macrophage phagosome are the target of many anti-microbial effector molecules. Although mitochondria-derived antimicrobial effectors such as reactive oxygen species (mROS) are reported to aid in bacterial killing, it is unclear how these effectors reach bacteria within the phagosomal lumen. To examine the crosstalk between mitochondria and phagosomes, we moni...

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Literature Corpus work: 16d4bbb2-bf4f-5fb8-bdff-fd77b3d5ce10
DOI: 10.1101/277004

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