Article

Multiplexed biochemical imaging reveals caspase activation patterns underlying single cell fate

2018-10-02

Abstract excerpt

The biochemical activities underlying cell-fate decisions vary profoundly even in genetically identical cells. But such non-genetic heterogeneity remains refractory to current imaging methods, because their capacity to monitor multiple biochemical activities in single living cells over time remains limited 1 . Here, we deploy a family of newly designed GFP-like sensors (NyxBits) with fast photon-counting electron...

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Literature Corpus work: 16a32973-83e2-5ba0-8ea1-ac87c4e5d011
DOI: 10.1101/427237

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