Article

Organotypic culture of normal, dysplastic and squamous cell carcinoma‐derived oral cell lines reveals loss of spatial regulation of CD44 and p75NTR in malignancy

2012-05-29

Abstract excerpt

Oral squamous cell carcinomas (OSCC) often arise from dysplastic lesions. The role of cancer stem cells in tumour initiation is widely accepted, yet the potential existence of pre‐cancerous stem cells in dysplastic tissue has received little attention. Cell lines from oral diseases ranging in severity from dysplasia to malignancy provide opportunity to investigate the involvement of stem cells in malignant progres...

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Identifiers and source

Literature Corpus work: 16648337-9b19-5134-89d5-baf1da957f59
DOI: 10.1111/j.1600-0714.2012.01170.x

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