Article

The association between knee synovial methylation and knee osteoarthritis in different ethnic populations from different altitude

2024-03-21

Abstract excerpt

<h4>Objective: </h4> To determine genome-wide DNA methylation profiles of knee cartilage from patients with osteoarthritis (OA) at different altitudes. <h4>Method: </h4> : Twenty-four synovial tissue samples were selected. OA synovial tissue samples were obtained from 10 Tibetan OA patients at high altitude and 8 Han OA patients at low altitude. Six normal synovial tissue samples were used as the control group. I...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 164c8905-939f-5b2c-bfa3-5f1d3adf0172
DOI: 10.21203/rs.3.rs-4000104/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The association between knee synovial methylation and knee osteoarthritis in different ethnic populations from different altitudeDOI 10.21203/rs.3.rs-4000104/v1Read

Quantitative analysis of DNA methylation-related proteins in patients with knee osteoarthritisSemantic proximity Read

Characterization of the Cartilage DNA Methylome in Knee and Hip OsteoarthritisSemantic proximity Read

Epigenomic differences between osteoarthritis grades in primary cartilageSemantic proximity Read

Epigenetic differences in human cartilage between mild and severe OASemantic proximity Read

Genome-wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritisSemantic proximity Read

DNA methylation in adaptation to high-altitude environments and pathogenesis of related diseasesSemantic proximity Read

Hypoxia induces transcription of DOT1L in articular cartilage to protect against osteoarthritisSemantic proximity Read

Chromatin accessibility landscape of articular knee cartilage reveals aberrant enhancer regulation in osteoarthritisSemantic proximity Read

The epigenomic landscape of primary tissues in osteoarthritis.Semantic proximity Read

Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritisSemantic proximity Read

Identification of Global DNA Methylation Signatures in Patients of High Altitude Induced Venous Thrombo-Embolism (HA-VTE)Semantic proximity Read

Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritisSemantic proximity Read