Article

Single-cell Transcriptomic Analysis of Systemic Autoinflammatory Diseases with Anti-TNFα Therapy

2022-11-30

Abstract excerpt

Systemic autoinflammatory diseases (SAIDs) are a group of rare diseases characterized by recurrent or continuous inflammation, typically accompanied by genetic variants. Good responses to anti-TNFα therapy were observed in SAIDs patients. However, the mechanisms underlying the disease flare and the response to TNFα blocking therapy have not been fully elucidated. Here, we use single-cell RNA sequencing technology...

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Literature Corpus work: 82ac000d-6c21-5c18-b14c-45e8389c0aa2
DOI: 10.1101/2022.11.29.518333

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