Article

Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein response

2025-11-13

Abstract excerpt

<title>Abstract</title> <p>Classic Hodgkin lymphoma (cHL) shares mutations with primary mediastinal B cell lymphoma (PMBL) but differs in histology, clinical behavior, and phenotype. To define transcriptional programs underlying these differences, we performed flow cytometric cell sorting and low-input RNA sequencing of Hodgkin and Reed-Sternberg (HRS) cells from eighteen primary tumors, paired intra-tumoral B ce...

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Literature Corpus work: 15ec4b2b-e991-5917-9662-530e92fce038
DOI: 10.21203/rs.3.rs-7957952/v1

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