Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single‐cell RNA sequencing of pediatric Hodgkin lymphoma to study the inhibition of T cell subtypes

1 Sept 2024

Abstract excerpt

Abstract Pediatric classic Hodgkin lymphoma (cHL) patients have a high survival rate but suffer from severe long‐term side effects induced by chemo‐ and radiotherapy. cHL tumors are characterized by the low fraction (0.1%–10%) of malignant Hodgkin and Reed–Sternberg (HRS) cells in the tumor. The HRS cells depend on the surrounding immune cells for survival and growth. This dependence is leveraged by current...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Immune Cell Function and Interaction
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39233904
DOI: 10.1002/hem3.149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single‐cell RNA sequencing of pediatric Hodgkin lymphoma to study the inhibition of T cell subtypesPMID 39233904Read ↗

Tumor-microenvironment and molecular biology of classic Hodgkin lymphoma in children, adolescents, and young adultsSemantic proximity Read ↗

Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein responseSemantic proximity Read ↗

Transcriptome sequencing of Hodgkin lymphoma Hodgkin and Reed-Sternberg cells reveals escape from NK cell recognition and an unfolded protein responseSemantic proximity Read ↗

The Evolving Knowledge on T and NK Cells in Classic Hodgkin Lymphoma: Insights into Novel Subsets Populating the Immune MicroenvironmentSemantic proximity Read ↗

Genetic risk and immune dysregulation of classic Hodgkin lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma: a multicentric studySemantic proximity Read ↗

Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cellsSemantic proximity Read ↗

Genome-scale spatial mapping of the Hodgkin lymphoma microenvironment identifies tumor cell survival factorsSemantic proximity Read ↗

Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling.Semantic proximity Read ↗

Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progressionSemantic proximity Read ↗

Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasionSemantic proximity Read ↗

Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin Lymphoma.Semantic proximity Read ↗

Novel insights into Hodgkin lymphoma biology by single-cell analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.