Article

The adapted Activity-By-Contact model for enhancer-gene assignment and its application to single-cell data

2022-01-28

Abstract excerpt

Identifying regulatory regions in the genome is of great interest for understanding the epigenomic landscape in cells. One fundamental challenge in this context is to find the target genes whose expression is affected by the regulatory regions. A recent successful method is the Activity-By-Contact (ABC) model (Fulco et al., 2019) which scores enhancer-gene interactions based on enhancer activity and the contact fr...

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Literature Corpus work: 15ea9606-c6f3-5e1e-bbb2-c4a7c7233fcc
DOI: 10.1101/2022.01.28.478202

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