Article

Differences in the inflammatory response and corticoid responsiveness of human lung macrophages and parenchymal explants exposed to cigarette smoke extracts

2025-03-24

Abstract excerpt

Smoking is the main cause of chronic obstructive pulmonary disease and is associated with corticosteroid resistance. Given the paucity of data on human lung preparations, macrophages (LMs) and parenchymal explants (LPEs) were exposed to cigarette smoke extract (CSE) in the presence or absence of lipopolysaccharide (LPS). Moreover, LMs and LPEs were treated with budesonide prior exposure to CSE or LPS. The levels o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 15e18933-7cac-5ed2-94dd-0def72278d67
DOI: 10.22541/au.174282481.17279538/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 9 closest

Differences in the inflammatory response and corticoid responsiveness of human lung macrophages and parenchymal explants exposed to cigarette smoke extractsDOI 10.22541/au.174282481.17279538/v1Read

Airway epithelial cell apoptosis and inflammation in COPD, smokers and nonsmokersSemantic proximity Read

Enhanced Lung Inflammatory Response in Whole-body Compared to Nose-only Cigarette Smoke-exposed MiceSemantic proximity Read

Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype.Semantic proximity Read

Investigation of corticosteroid responsiveness in airway smooth muscle cells of severe asthmaSemantic proximity Read

Microenvironmental stimuli induce different macrophage polarizations in experimental models of emphysemaSemantic proximity Read

Time Course of the Phenotype of Blood and Bone Marrow Monocytes and Macrophages in the Lung after Cigarette Smoke Exposure In Vivo.Semantic proximity Read

Challenges for inhaled drug discovery and development: Induced alveolar macrophage responsesSemantic proximity Read

Electronic cigarette vapour increases virulence and inflammatory potential of respiratory pathogensSemantic proximity Read

Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice.Semantic proximity Read