Article

Baseline gene expression and dynamic endocrine therapy use in ER+ breast cancer: associations with recurrence in a real-world cohort

2026-06-30

Abstract excerpt

<title>Abstract</title> <p> Endocrine therapy (ET) selection in estrogen receptor–positive breast cancer (ER + BC) is guided by menopausal status and tolerability rather than tumor biology, despite substantial heterogeneity in recurrence. We hypothesized that baseline gene expression differentially associates with recurrence depending on initial ET class. In a retrospective cohort of 74 ER+/HER2– patients treate...

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Literature Corpus work: 15c06df3-4d4f-50b7-894d-117d3d7540ab
DOI: 10.21203/rs.3.rs-9998817/v1

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