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Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers

5 Aug 2019

Abstract excerpt

BACKGROUND: Approximately two thirds of patients with localized triple-negative breast cancer (TNBC) harbor residual disease (RD) after neoadjuvant chemotherapy (NAC) and have a high risk-of-recurrence. Targeted therapeutic development for TNBC is of primary significance as no targeted therapies are clinically indicated for this aggressive subset. In view of this, we conducted a comprehensive molecular analysis...

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PMID: 31383035
DOI: 10.1186/s13058-019-1171-7

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