Article

Integrative analysis of pre-treatment RNA expression signatures and recurrent genomic alterations: Link to menopausal status, short-term endocrine therapy response and disease-free survival in luminal breast cancer

2025-06-13

Abstract excerpt

<h4>Background</h4> Endocrine therapy with tamoxifen (TAM) or aromatase inhibitors (AI) is an effective treatment for patients with estrogen receptor-positive, HER2-negative luminal breast cancer. However, many patients do not respond to this therapy, leading to disease recurrence. This study aimed to identify baseline clinical, molecular, and genetic features associated with menopause status, primary endocrine t...

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Literature Corpus work: e092bc18-8a2f-5b42-8cd5-3d121108dc67
DOI: 10.1101/2025.06.11.25329354

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Integrative analysis of pre-treatment RNA expression signatures and recurrent genomic alterations: Link to menopausal status, short-term endocrine therapy response and disease-free survival in luminal breast cancerDOI 10.1101/2025.06.11.25329354Read

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